Breast cancer is global female health problem worldwide. Most of the currently used agents for breast cancer treatment have toxic side-effects. Ginseng root, an oriental medicine, has many health benefits and may exhibit direct anti-cancer properties. This study was performed to assess the effects of ginseng on breast cancer cell lines.
For more details please see report at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5454704/.
Meanwhile, here are extracts from the report...
"To test the effect of ginseng extract on the apoptotic pathway in different breast cancer cell lines, first the anti-proliferative effects of ginseng extract were assessed by MTT on breast cancer cell lines cultured with increasing concentrations of ginseng extract for periods of 24, 48, or 72 hours. Breast cancer cells were seeded in triplicates into 96 well plates and treated with different concentrations of ginseng extract (0.5, 1, 1.5, 2 and 2.5 mg/well) for 24 h,48h and 72 h and viable cells were measured by MTT assay."
"Breast cancer is the most common leading cause of death among women due to aggressiveness and distant metastases. Breast cancer is a global health problem. Triple negative breast cancers (TNBCs) are an aggressive subtypes of breast cancers with no effective targeted therapies and cannot be treated with endocrine or anti-HER2 targeted therapies. At the present time more attentions have been directed to natural products in cancer treatment. Natural products showed several anticancer effects. Several studies have shown the anticancer effect of ginseng against several type of cancers. The present study investigates the effect of ginseng extract on breast cancer cell line."
"The current study revealed that ginseng inhibits breast cancer cells growth in a dose-dependent manner. The decreased cell numbers in the treated groups may be due to apoptosis and/or growth inhibition."
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